Fatty Acid ethyl esters in scalp, pubic, axillary, beard and body hair as markers for alcohol misuse.
نویسندگان
چکیده
AIMS This study examined the possibility of using hair samples other than scalp hair for analysis of fatty acid ethyl esters (FAEE) as markers for alcohol misuse. METHODS Samples of scalp and pubic hair and, if available, axillary, beard and body hair of one teetotaller, five moderate social drinkers and 22 fatalities were analysed for FAEE by head-space solid-phase microextraction and gas chromatography-mass spectrometry. The sum of the concentrations of ethyl myristate, ethyl palmitate, ethyl oleate and ethyl stearate (C(FAEE)) in the hair samples was compared with information about the drinking behaviour of the individuals. RESULTS Although there were large differences in the analyte concentrations in hair from different sites in the same individual, cases of chronic excessive alcohol consumption were characterized by C(FAEE) > 1.0 ng/mg in almost all samples. CONCLUSION FAEE concentrations in hair other than scalp hair can be used as markers of chronic alcohol misuse.
منابع مشابه
2014 consensus for the use of alcohol markers in hair for assessment of both abstinence and chronic excessive alcohol consumption.
1.1 The direct determination of ethanol itself in hair is not possible due to its volatility and its potential absorption from external sources. Instead, the minor ethanol metabolites ethyl glucuronide (EtG) and/or fatty acid ethyl esters (FAEEs) can be measured in hair as direct markers of alcohol consumption. 1.2 In this consensus FAEEs are defined as: ethyl myristate, ethyl palmitate, ethyl ...
متن کاملWorkplace alcohol testing program by combined use of ethyl glucuronide and fatty acid ethyl esters in hair.
AIMS The applicability of fatty acid ethyl esters (FAEEs) and ethyl glucuronide (EtG) in hair in a workplace alcohol testing program was investigated. METHODS A total of 78 hair samples from employees in jobs with a high endangering potential were tested for EtG and FAEEs. In most cases excessive drinking was suspected. For 59 of these cases additional data of the traditional alcohol markers ...
متن کاملA SPME-GC/MS procedure for the determination of fatty acid ethyl esters in hair for confirmation of abstinence test results.
Fatty acid ethyl esters (FAEE), direct metabolites of ethanol, are suitable alcohol markers that can be detected in different tissues. The determination of FAEE in hair can help to evaluate social and excessive alcohol consumption. Due to the presence of FAEE in the hair of teetotalers, proving alcohol abstinence seems to be impossible. To verify these results, an solid phase micro extraction-g...
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A 62-year old man with HIV was referred to us for evaluation of underarm pruritus for one month. Previous providers had recommended pramoxine and ketoconazole creams, which did not improve the condition. He reported intimate contact with one male partner. Examination revealed an ill-defined erythematous patch of his left axilla with numerous cream-colored eggs cemented to the base of axillary h...
متن کاملFatty acid ethyl esters in hair as markers of alcohol consumption. Segmental hair analysis of alcoholics, social drinkers, and teetotalers.
BACKGROUND Fatty acid ethyl esters (FAEEs) are products of nonoxidative ethanol metabolism. After incorporation in hair, they should be suitable long-term markers of alcohol abuse. METHODS Hair samples from 19 alcoholics in a treatment program, 10 fatalities with verified excessive alcohol consumption, 13 moderate social drinkers who consumed up to 20 g ethanol/day, and 5 strict teetotalers w...
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ورودعنوان ژورنال:
- Alcohol and alcoholism
دوره 38 2 شماره
صفحات -
تاریخ انتشار 2003